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美国范德堡大学

日期:2018-03-06

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美国范德堡大学(Vanderbilt University): 流行病学中心

       1997年,上海市肿瘤研究所流行病学中心与美国范德堡大学流行病学中心郑苇、舒晓鸥两位教授展开合作交流。随着双方研究交流的深入,联合申请了多项大规模、全人群流行病学研究课题,主要是上海男性健康队列和上海女性健康队列。已累计发表期刊论文200余篇,近5年的代表性论文有New England Journal of Medicine 1篇,Nature Genetics 11篇,JAMA Internal Medicine 1篇,Journal of Clinical Oncology 2篇,J Natl Cancer Inst  2篇,BMJ 1篇,Nature Communications 2篇,PLoS Medicine 1篇,Gut 1篇,Int J Epidemiol 4篇。累计获得科研经费6000多万人民币。


合作发表的高质量论文:

1. Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med.  2011, 364(8): 719-729. 

2. Genome-wide association study identifies a common variant associated with risk of endometrial cancer. Nat Genet 2011, 43(5): 451-454.

3.  Association of adult height and its components with mortality: a report from cohort studies of 135,000 Chinese women and men. Int J Epidemiol 2011, 40(6): 1715-1726.

4. Urinary isoflavonoids and risk of coronary heart disease. Int J Epidemiol 2012, 41(5): 1367-1375.

5. Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet 2012, 44(12): 1330-1335.

6. Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Nat Genet 2012, 44(11): 1231-1235.

7. Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet 2012, 44(6): 651-658.

8. Meta-analysis identifies common variants associated with body mass index in East Asians. Nat Genet 2012, 44(3): 307-311.

9. Genome-Wide Association Study in East Asians Identifies Novel Susceptibility Loci for Breast Cancer. PLoS Genetics 2012, 8(2): e1002532.

10. Type Ⅰand Ⅱ endometrial cancers: have they different risk factors? J Clin Oncol 2013, 31(20): 2607-2618.

11. Prediagnosis soy food consumption and lung cancer survival in women. J Clin Oncol 2013, 31(12): 1548-1553.

12. Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. Nat Genet 2013, 45(2):191-196.

13. Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet 2013, 45(1): 72-77.

14. A common deletion in the APOBEC3 genes and breast cancer risk. J Natl Cancer Inst 2013, 105(8): 573-579.

15. Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: pooled analysis of prospective data from the Asia Cohort consortium. BMJ 2013, 347: f5446.

16. Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology 2013, 144(4): 799-807.

17. Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. Nat Commun 2013, 4:1627.

18. Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. Nat Genet 2014, 46(9): 1001-1006.

19. Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1. Nat Genet 2014, 46(8): 886-890.

20. Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. Nat Genet 2014, 46(6): 533-542.

21. Burden of total and cause-specific mortality related to tobacco smoking among adults aged ≧45 years in Asia: a pooled analysis of 21 cohorts. PLoS medicine 2014, 11(4): e1001631.

22. Cohort Profile: The Shanghai Men’s Health Study. Int J Epidemiol 2015, 44(3): 810-818.

23. Anthropometry and head and neck cancer: a pooled analysis of cohort data. Int J Epidemiol 2015, 44(2): 673-681.

24. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nat Genet 2015, 47(11): 1282-1293.

25. Prospective evaluation of the association of nut/peanut consumption with total and cause-specific mortality. JAMA Intern Med 2015, 175(5): 755-766.

26. Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types. J Natl Cancer Inst 2015, 107(12): djv279.

27. Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun 2015, 6: 7138

28. Identification of new susceptibility loci for gastric non-cardia adenocarcinoma:  pooled results from two Chinese genome-wide association studies. Gut, 2017, 66(4):581-587. 


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