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Cooperation partners




美国匹兹堡大学(University of Pittsburgh): 流行病学研究中心、 药学系

       1987年,上海市肿瘤研究所流行病学中心与美国南加州大学流行病学研究中心的袁剑敏教授合作开展了上海男性血清库的队列研究合作,后来因负责人的工作流动原因,继而与明尼苏达大学,再到匹兹堡大学进行合作,科研经费多达2000万人民币。期间联合发表论文70余篇,其中不乏多篇高质量的SCI论文发表于New England Journal of Medicine(1篇),JAMA(1篇),JAMA Internal Medicine(1篇),Nature Genetics(1篇),BMJ(1篇)和International Journal of Cancer(6篇)。2009年,肿瘤微环境研究组覃文新教授与匹兹堡大学药学系谢文教授在肝病研究领域开展合作,共同培养研究生,联合发表研究论文。至今已合作发表Hepatology论文2篇、Journal of Hepatology论文1篇。



1. Morbidity and mortality in relation to cigarette smoking in Shanghai, China. JAMA 1996; 275: 1646-50.

2. Non-dietary risk factors for nasopharyngeal carcinoma in Shanghai, China. Int J Cancer 2000, 85(3): 364-9.

3. Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China. Int J Cancer 2000, 85(3): 358-63.

4. Dietary soy and increased risk of bladder cancer: a prospective cohort study of men in Shanghai, China.Int J Cancer 2004, 112(2): 319-23.

5. Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and gastric cancer risk: a prospective study of men in Shanghai, China. Int J Cancer 2009, 125(11): 2652-9

6. Association between body-mass index and risk of death in more than 1 million Asians. N Eng J M 2011, 364(8): 719-729.

7. Activation of liver X receptor increases acetaminophen clearance and prevents its toxicity in mice. Hepatology. 2011;54(6):2208-17.

8. Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: pooled analysis of prospective data from the Asia Cohort consortium. BMJ 2013, 347: f5446.

9. Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations.Nat Genet 2014, 46(9): 1001-1006.

10. Inflammatory regulation of steroid sulfatase: A novel mechanism to control estrogen homeostasis and inflammation in chronic liver disease. J Hepatol. 2016;64(1):44-52.

11. Tobacco-specific N-nitrosamines and polycyclic aromatic hydrocarbons in cigarettes smoked by the participants of the Shanghai Cohort Study. Int J Cancer 2016, 139(6): 1261-9.

12. Genetic determinants of cytochrome P450 2A6 activity and biomarkers of tobacco smoke exposure in relation to risk of lung cancer development in the Shanghai cohort study. Int J Cancer 2016, 138(9): 2161-71.

13. Farnesoid X receptor ablation sensitizes mice to hepatitis b virus X protein-induced hepatocarcinogenesis. Hepatology. 2017 ;65(3):893-906.

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