一、研究方向

癌症生物学起源

肿瘤细胞命运改变

肿瘤免疫微环境

二、代表性论文

1.    Wang H*, Xiang D*, Liu B, et al., Li Z#, Livingston D#. Inadequate DNA damage repair promotes mammary transdifferentiation leading to BRCA1 breast cancer. Cell 2019; 178(1):135-151.e19. (*共同第一作者)

2.    He A#, Huang Y, Cheng W, Zhang D, He W, Bai Y, Gu C, Ma Z, He Z, Si G, Chen B, Breault T.D, Dong M, Xiang D#. Organoid culture system for patient-derived osteosarcoma tissue. Medical Oncology 2020; 37(11):105. (#共同通讯作者)

3.    He A.#, Ma L., Huang Y., Zhang H, Duan W, Li Z, Fei T, Yuan J, Wu H, Liu L, Bai Y, Dai W, Wang Y, Li H, Sun Y, Wang Y, Wang C, Yuan T, Yang Q, Tian S, Dong M, Sheng R#, and Xiang D#. CDKL3 promotes osteosarcoma progression by activating Akt/PKB. Life Science Alliance 2020; 3; 5: 1-16. (#共同通讯作者)

4.    Xiang D, Tao L, Li Z. Modeling Breast Cancer Via an Intraductal Injection of Cre-Expressing Adenovirus into the Mouse Mammary Gland. J. Vis. Exp. 2019; 7; (148).

5.    Xiang D, Shigdar S, Bean A, Bruce M, Yang W, Mathesh M, Wang T, Yin W, Tran Ha-Lien P, AlShamaileh H, Barrero RA, Zhang P, Li Y, Kong L, Liu K, Zhou S, Hou Y, He A, and Duan W. Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery. Theranostics 2017; 7 (17): 4071.