1986年毕业于安徽医科大学获学士学位，1989年毕业于上海医科大学获医学硕士学位，现为复旦大学公共卫生学院博士生导师、上海交通大学医学院博士生导师，癌基因及相关基因国家重点实验室课题组长。享受国务院政府特殊津贴（2000年）。

1989-2000年间主要参与和负责了下列流行病学研究课题，例如上海市肿瘤登记处数据管理和统计分析、癌症发病死亡率时间趋势分析、全人群癌症生存率分析、常见癌症病例对照研究（如肺癌、膀胱癌、子宫内膜癌、大肠癌）、膳食和体力活动调查表信度和效度研究、WHO癌症合作中心相关工作等。2000年以来，主要负责一些国际合作项目，例如上海男性健康队列、上海女性健康队列等。此外，2008-2015年主持了国家科技重大专项的子课题（十一五和十二五课题）两项。目前正负责国家重点研发计划项目子项目一项（2016-2020年），参与科技部973项目一项（2015-2019年）。

已在国内外学术期刊上发表了460余篇科研论文，包括中文期刊文章160余篇，英文期刊文章300余篇；其中SCI期刊通讯作者文章46篇（合计IF约195）；此外，作为论文合作者之一，发表下列SCI期刊文章30余篇（如Lancet Oncol、J Natl Cancer Inst、J Clin Oncol、BMJ、N Engl J Med、JAMA Intern Med、Nat Genet、Nat Commun、Gut、Gastroenterology、Plos Med、Diabetes Care等）。已累计培养流行病学与卫生统计学专业研究生30名（博士6名，硕士24名），并带教和培训外籍研究生5位（印尼2人、法国1人和美国2人）。

1．肿瘤描述流行病学

2．流行病学现场工作和生物样本资源管理

3．肿瘤等慢性病的病因学探讨

4．生物统计方法及其应用

近5年代表性论文

1.      Shu X, Xiang YB, Rothman N, Yu D, Li HL, Yang G, Cai H, Ma X, Lan Q, Gao YT, Jia W, Shu XO, Zheng W. Prospective study of blood metabolites associated with colorectal cancer risk. Int J Cancer. 2018 Feb 26. doi: 10.1002/ijc.31341. [Epub]PMID:29479691

2.      Zhang QL, Zhao LG, Li HL, Gao J, Yang G, Wang J, Zheng W, Shu XO, Xiang YB. The joint effects of major lifestyle factors on colorectal cancer risk among Chinese men: a prospective cohort study. Int J Cancer 2018; 142(6): 1093-1101.

3.      Yang Y, Gao J, Tan YT, Li HL, Wang J, Ma X, Zheng W, Shu XO, Xiang YB. Individual and combined effects of hepatitis B surface antigen and viral load on liver cancer risk among hepatitis B carriers. J Gastroen Hepatol 2017 Oct 24. doi: 10.1111/jgh.14032.

4.      Zhang QL, Zhao LG, Zhang W, Li HL, Gao J, Han LH, Zheng W, Shu XO, Xiang YB. Combined impact of known lifestyle factors on total and cause-specific mortality among Chinese men: a prospective cohort study. Sci Rep 2017; 7(1):5293.

5.      Ma X, Yang Y, Li HL, Zheng W, Gao J, Zhang W, Yang G, Shu XO, Xiang YB. Dietary trace element intake and liver cancer risk: results from two population-based cohorts in China. Int J Cancer 2017; 140(5):1050-1059.

6.      Yang Y, Gao J, Li HL, Shu XO, Zhang W, Ma X, Tan YT, Rothman N, Gao YT, Chow WH, Zheng W, Xiang YB. Dose-response association between hepatitis B surface antigen levels and liver cancer risk in Chinese men and women. Int J Cancer 2016; 139(2):355-62.

7.      Sun JW, Zhao LG, Yang Y, Ma X, Wang YY, Xiang YB. TV time and all-cause mortality: a meta-analysis of cohort studies. Am J Epidemiol 2015; 182(11):908-16.

8.      Yang Y, Zhao LG, Wu QJ, Ma X, Xiang YB. Association between dietary fiber and lower risk of all-cause mortality: a meta-analysis of cohort studies. Am J Epidemiol. 2015; 181(2):83-91.

9.      Wu QJ, Yang G, Zheng W, Li HL, Gao J, Wang J, Gao YT, Shu XO, Xiang YB. Pre-diagnostic cruciferous vegetables intake and lung cancer survival in Chinese women. Sci Rep. 2015; 5:10306.

10.   Shu XO, Li H, Yang G, Gao J, Cai H, Takata Y, Zheng W, Xiang YB. Cohort Profile: The Shanghai Men’s Health Study. Int J Epidemiol 2015; 44(3):810-8.

11.   Wu QJ, Xiang YB, Yang G, Li HL, Lan Q, Gao YT, Zheng W, Shu XO, Fowke JH. Vitamin E intake and the lung cancer risk among female nonsmokers: A report from the Shanghai Women's Health Study. Int J Cancer 2015; 136(3):610-7.

12.   Vogtmann E, Shu XO, Li HL, Chow WH, Yang G, Ji BT, Cai H, Yu C, Gao YT, Zheng W, Xiang YB. Cholelithiasis and the risk of liver cancer: results from cohort studies of 134,546 Chinese men and women. J Epidemiol Community Health 2014; 68(6):565-70.

13.   Yang Y, Wu QJ, Xie L, Chow WH, Rothman N, Li HL, Gao YT, Zheng W, Shu XO, Xiang YB. Prospective cohort studies of association between family history of cancer and risk of liver cancer. Int J Cancer 2014; 135(7):1605-14.

14.   Gao J, Xu HL, Gao S, Zhang W, Tan YT, Rothman N, Purdue M, Gao YT, Zheng W, Shu XO, Xiang YB. Genetic variants of NFKB1 and NFKBIA and liver cancer risk: a nested case-control study in Shanghai, China. BMJ Open 2014;4(2):e004427. doi: 10.1136/bmjopen-2013-004427.

15.   Wu QJ, Wang J, Gao J, Zhang W, Han LH, Gao S, Gao YT, Ji BT, Zheng W, Shu XO, Xiang YB. Urinary isothiocyanates level and liver cancer risk: a nested case-control study in Shanghai, China. Nutr Cancer 2014; 66(6):1023-9.

16.   Li H, Yang G, Xiang YB, Gao J, Zhang X, Zheng W, Gao YT, Shu XO. Body weight, fat distribution and colorectal cancer risk: a report from cohort studies of 134255 Chinese men and women. Int J Obes (Lond) 2013; 37(6):783-9.

17.   Zhang W, Xiang YB, Li HL, Yang G, Cai H, Ji BT, Gao YT, Zheng W, Shu XO. Vegetable-based dietary pattern and liver cancer risk: results from the Shanghai Women's and Men's Health Studies. Cancer Sci 2013; 104(10):1353-61.

18.   Zhang W, Shu XO, Li HL, Yang G, Cai H, Ji BT, Gao J, Gao YT, Zheng W, Xiang YB. Vitamin intake and liver cancer risk: a report from two cohort studies in China. J Natl Cancer Inst 2012; 104(15):1174-1182

19.   Wu QJ, Xie L, Zheng W, Vogtmann E, Li HL, Yang G, Ji BT, Gao YT, Shu XO, Xiang YB. Cruciferous vegetables consumption and the risk of female lung cancer: a prospective study and a meta-analysis. Ann Oncol 2013; 24(7):1918-24.

20.   Wu QJ, Yang Y, Vogtmann E, Wang J, Han LH, Li HL, Xiang YB. Cruciferous vegetables intake and the risk of colorectal cancer: a meta-analysis of observational studies. Ann Oncol 2013; 24(4):1079-87.

21.   Yang WS, Shu XO, Li HL, Gao J, Yang G, Cai H, Ji BT, Rothman N, Gao YT, Zheng W, Xiang YB. Prospective evaluation of type 2 diabetes mellitus and liver cancer risk in Chinese men and women. Ann Oncol 2013; 24(6):1679-85.

22.   Vogtmann E, Li HL, Shu XO, Chow WH, Ji BT, Gao J, Zhang W, Gao YT, Zheng W, Xiang YB. Glycemic index, glycemic load and carbohydrates and risk of primary liver cancer among Chinese men and women. Ann Oncol 2013; 24(1):238-44.

23.   Yu D, Zhang X, Xiang YB, Yang G, Li H, Gao YT, Zheng W, Shu XO. Adherence to dietary guidelines and mortality: a report from prospective cohort studies of 134,000 Chinese adults in urban Shanghai. Am J Clin Nutr 2014; 100(2):693-700. 

24.   Yu D, Zhang X, Xiang YB, Yang G, Li H, Fazio S, Linton M, Cai Q, Zheng W, Gao YT, Shu XO. Association of soy food intake with risk and biomarkers of coronary heart disease in Chinese men. Int J Cardiol 2014;172(2):e285-7.

25.   55.  Luu HN, Blot WJ, Xiang YB, Cai H, Hargreaves MK, Li H, Yang G, Signorello L, Gao YT, Zheng W, Shu XO. Prospective Evaluation of the Association of Nut/Peanut Consumption With Total and Cause-Specific Mortality. JAMA Intern Med 2015; 175(5):755-66.

26.   Wang N, Zhang X, Xiang YB, Li H, Yang G, Gao J, Zheng W, Shu XO. Associations of Tai Chi, Walking, and Jogging With Mortality in Chinese Men. Am J Epidemiol 2013; 178(5):791-6.

27.   Long J, Delahanty RJ, Li G, Gao YT, Lu W, Cai Q, Xiang YB, Li C, Ji BT, Zheng Y, Ali S, Shu XO, Zheng W. A Common Deletion in the APOBEC3 Genes and Breast Cancer Risk. J Natl Cancer Inst 2013; 105(8):573-9.

28.   Takata Y, Xiang YB, Yang G, Li H, Gao J, Cai H, Gao YT, Zheng W, Shu XO. Intakes of Fruits, Vegetables, and Related Vitamins and Lung Cancer Risk: Results from the Shanghai Men's Health Study (2002-2009). Nutr Cancer 2013; 65(1):51-61.

29.   Jia WH, Zhang B, Matsuo K, Shin A, Xiang YB, Jee SH, Kim DH, Ren Z, Cai Q, Long J, Shi J, Wen W, Yang G, Delahanty RJ; Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO); Colon Cancer Family Registry (CCFR), Ji BT, Pan ZZ, Matsuda F, Gao YT, Oh JH, Ahn YO, Park EJ, Li HL, Park JW, Jo J, Jeong JY, Hosono S, Casey G, Peters U, Shu XO, Zeng YX, Zheng W. Genome-wide association analyses in east Asians identify new susceptibility loci for colorectal cancer. Nat Genet 2013; 45(2):191-6.

30.   Tao L, Xiang YB, Chan KK, Wang R, Gao YT, Yu MC, Yuan JM. Cytochrome P4501A2 phenotype and bladder cancer risk: The Shanghai bladder cancer study. Int J Cancer 2012; 130(5):1174-83.

流行病学研究室目前主要针对上海地区一些常见恶性肿瘤或发病率变化迅速的恶性肿瘤开展危险因素的探索，包括肿瘤营养流行病学、遗传流行病学和分子流行病学的研究课题。科研工作的重点之一是维护两个长期随访的健康人群队列，队列中所有对象的基线和随访的流行病学资料均已计算机化；基线调查中所采集的生物标本，置于均超低温环境保存。研究室现有在职科研人员12人，其中高级职称4名（研究员1名、副研究员1名、副主任技师2名），助理研究员（中级职称）6人。协助研究室科研人员开展现场工作、数据编码、质量控制、计算机数据管理、生物样品采集的聘用专职人员20余人。

                                                                       研究组成员

研究组学生